Assembly of RNPs: help needed

Assembly of RNPs: help needed.

In 1968 the Nomura lab in Madison made an astonishing observation: when ribosomal proteins were mixed under appropriate conditions with 16S rRNA, fully functional ribosomal 30S subunits were formed. Along with the subsequent total reconstitution of 50S subunits, it was established that even entire ribosomes could be assembled in vitro from their constituents. Neither energy in the form of nucle...

Synthesis and Assembly of the Box C1D Small Nucleolar RNPs

Policy Help Needed, Experience Required

1 Objectives. There is a shift toward a “health in all policies” approach in public health; however, most practitioners are not equipped with the necessary knowledge or skills to engage in and practice policy. This study explores how public health professionals can become policy practitioners and better engage in the policy process. This article also provides recommendations for training progra...

The SMN complex: an assembly machine for RNPs.

In eukaryotic cells, the biogenesis of spliceosomal small nuclear ribonucleoproteins (snRNPs) and likely other RNPs is mediated by an assemblyosome, the survival of motor neurons (SMN) complex. The SMN complex, composed of SMN and the Gemins (2-7), binds to the Sm proteins and to snRNAs and constructs the heptameric rings, the common cores of Sm proteins, on the Sm site (AU(56)G) of the snRNAs....

Help needed on hot water burns.